The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| 型号名称 | QSight 420 LC/MS/MS |
|---|
QSight 400与QSight LX50超高效液相色谱仪联用，为实验室提供全新的技术体验，用于分析复杂的食品、药品类和环境类样品。拥有超高的灵敏度和样品通量，实验室可轻松、快速和高效地应对最严格的法规监管要求。
Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements
在养蜂业中，磺胺类药物是治疗美国和欧洲臭虫病（一种感染蜜蜂的疾病）的最常用抗生素。本应用说明介绍了QSight 200系统如何为蜂蜜中磺胺类药物的分析提供一个非常灵敏和可靠的平台。
水溶性维生素（WSV）主要由维生素B复合物组成，是许多食品的基本成分，尤其是在婴儿配方食品中。在分析强化食品时，由于需要符合每日的摄入量，维生素的浓度范围很广，这一点尤其具有挑战性。本应用介绍了一种LC-MS/MS方法，用于婴儿配方食品中B族维生素的高效、常规和稳定的色谱分析。很宽浓度范围内的八种水溶性维生素被鉴定出来，并在4分钟内定量。结果表明，保留时间重复性好，该方法能够在0.5 ppb的浓度下检测维生素B12，远低于婴儿配方奶粉中预期水平的约2 ppb。
随着一些美国的州和省通过了药用和娱乐用途合法化的新法规，大麻浓缩物和CBD产品（食用食品、主题食品、电子烟产品等）的使用越来越受欢迎。确保大麻产品中杀虫剂和真菌毒素水平低于监管水平的测试至关重要，然而，大麻浓缩物基质存在许多分析挑战，包括样品基质效应更高和样品中大麻素浓度增加。在本应用说明中，提出了一种用于分析大麻浓缩物基质中66种农药（包括通常通过GC/MS/MS分析的疏水性和含氯农药）和5种真菌毒素的LC/MS/MS方法。利用配置有APCI和ESI双源的QSight®420 LC/MS/MS仪器，分析回收率良好且检测限低于加利福尼亚州大麻法规规定的标准。 ...
以猪肉特有的三种肽为生物标志物，建立了一种选择性、灵敏的LC/MS/MS快速鉴定和分析肉样的方法。优化后的样品制备方法简单易行，可用于生、熟、加工肉制品的分析。该方法可以在1%w/w（10mg/g）的阈值检测范围内选择性地检测各种食品猪肉中的肽，因此该方法可用于清真食品（或猪肉相关食品）样品的分析。
塑料是当今全球使用量最多的材料之一。它们已广泛融入现代工业和商业生活方式，几乎对每类产品都做出了不可替代的重大贡献。
您将在本纲要中了解聚合物、塑料、橡胶和先进材料的广泛应用，以及这些应用如何简化您的工作并提升效率。
丙烯酰胺是一种可能致癌的有机化合物，存在于一些高温烹调的食物中。它源于氨基酸天冬酰胺和葡萄糖发生美拉德反应。2002年，在炸薯条和烤面包中发现了丙烯酰胺。这种化合物现在也在一些其他食物中被发现，如咖啡、黑橄榄、干梨和花生。结果是世界卫生组织立即限制了它在食品中的存在。
最近在欧洲召回受污染的鸡蛋引起了对氟虫腈中毒的严重健康担忧。氟虫腈是一种剧毒杀虫剂，用于保护农作物。美国环保署已将氟虫腈列为C组致癌物。在这项研究中，我们描述了一种快速、可靠的分析方法，采用PerkinElmer QSight 200系列LC/MS/MS三重四极杆仪器对氟虫腈及其代谢物进行鉴定。结果表明，该方法具有极佳的回收率、线性、重现性和超高灵敏度。三步法样品制备过程快速简便，LC/MS/MS分析时间可在6分钟内完成，所有分析物的分离度都很高。
独特层流气离子导向技术UHPLC-ESI-MS/MS分析浆果中目标农药残留
In this study we show two methods for the analysis of over 30 antibiotics and veterinary drugs in milk regulated by the Food Safety and Standards Authority of India (FSSAI). For polar analyte analysis, such as aminoglycoside antibiotics (apramycin, spectinomycin, and neomycin) in milk, a mixed mode ...
This application note highlights the LC/MS/MS analysis of PFAS compounds according to the European Union Water Framework Directive 2020/2184. It demonstrates how the PerkinElmer QSight® 420 LC/MS/MS System using a large volume direct injection can determine and quantify the latest 20 PFAS compounds ...
Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...
Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through contami ...
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
A simple and sensitive method for the simultaneous determination of plant growth regulators
Several directives throughout the EU provide guidance on environmental quality standards for water, and define more than 30 priority substances as significant risk to humans. Many of the monitoring limits within these directives are set at low µg/L (ppb) levels, and as such, require highly sensitive ...
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
With routine labs tasked with the analysis of larger and larger target lists, and with greater numbers of samples requiring analysis, we deployed simple sample preparation protocols such as solvent extraction to meet the need of high sample throughput with lower cost. In this work, we demonstrate ho ...
Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade t ...
Cyanotoxins often exist intracellularly in cyanobacteria and are released into the water when cells die. Blooms caused by cyanobacteria can be harmful to the human health, animals, and the environment. Microcystin-LR (MC-LR) is one of the most common cyanotoxins and ingestion will cause negative hum ...
Since 2003 the usage of azo and non-azo dyes for food coloring has been declared as illegal by many of the food international authorities across the globe. That is because these substances such as Sudan I,II,III,IV and Rhodamine B, are potentially carcinogens and genotoxin in nature. As of now, no o ...
Haloacetic acids (HAAs) are a class of undesired by-products resulting from the reaction of chlorinated disinfectants with natural organic matter in water, Which is known to be carcinogenic. The Japan Ministry of Health revised the inspection method for HAAs, which led to expansion of the analytical ...
Simultaneous detect and quantify cortisol and cortisone in urine using the QSight 200 series mass spectrometer coupled with a commercially available kit.
Mycotoxins are toxic secondary metabolites produced by various fungal species growing in foods and animal feeds. To minimize risk and protect consumers, mycotoxin levels in foods and/or feeds have been regulated by agencies in many countries around the world. A number of analytical methods for the d ...
Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fire-fighting foams, water proofing treatments for clothing and furniture, nonstick cookware, and paper. PFAS’ are thermally and chemically st ...
This application note outlines a new workflow with one instrument platform (LC/MS/MS) method that is ideal for simultaneous analysis of pesticide and mycotoxins residue in cannabis. This application note demonstrates the performance of a LC/MS/MS ESI and APCI method with a single solvent extraction ...
This application note describes a novel LC/MS/MS method with dual ESI and APCI source for analysis of different pesticides and mycotoxins residues regulated by seven different states in cannabis samples as of June 2021. The straightforward sample preparation procedure allows to achieve short sample ...
Estrogen plays an important role in the human body, but excess concentrations of endogenous estrogens, a known endocrine disrupting compound (EDC), in urine have been linked to the development and growth of breast cancer and tumors in females. Endogenous estrogens, including estrone (E1), 17ß-estrad ...
EU water policies are reevaluated on a consistent basis to ensure water sources do not contain contaminants at levels above regulatory levels. As regulations are reviewed, regulatory limits are often lowered, and analytical techniques must adapt to meet the new stringent requirements. In this applic ...
Growing health concerns regarding PFAS and their prevalence in consumer goods and the environment indicate a critical need to execute existing and upcoming regulatory methods simply and reliably on commercially available instrumentation. The United States Environmental Protection Agency (EPA) has es ...
Per- and polyfluoroalkyl substances (PFAS) are a diverse group of synthetic organic compounds which have been utilized as aqueous film forming foams (AFFF) for firefighting purposes, and as stain and water resistant coatings on a number of consumer products such as clothing, furniture or cookware. P ...
This application note details an online-SPE-LC/MS/MS method for the determination of polycyclic aromatic hydrocarbons (PAHs) in drinking water samples which reaches the low detection levels required by EU regulations. The method couples the SP50 UHPLC system to the QSight® 400 series triple-quad mas ...
Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial
Per- and polyfluoroalkyl substances (PFAS) have gained significant attention as an emerging environmental and safety threat in the United States. Since the 1940s, PFAS are ubiquitous in industrial usage due to their chemical stability, thermal stability, and high resistance to degradation. Bioaccumu ...
