The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| 型号名称 | QSight 420 LC/MS/MS |
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Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and the effects that they can have on human health. Due to their inert nature, PFASs are persistent organic pollutants and have been found to ac ...
Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.
With our extended portfolio of cannabis testing products featuring best-in-class sample homogenization platforms, ICP-MS, LC/MS-MS, Headspace-GCMS, UHPLC and FTIR instruments and consumables, we help drive analytical best practices and operating procedur
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.
Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.
When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.
The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.
In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing
In this latest webinar, LC–MS/MS PerkinElmer expert Dr. Avinash Dalmia describes how LC–MS/MS based systems and methods can overcome the challenges associated with the analysis of pesticides and mycotoxins regulated by Colorado state in hemp with dual ES
Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza
PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis.
Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a
In this podcast, we meet with Simone Rumph, a first generation college student, to discuss her research on post-mortem drug identification.
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..
When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.
The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC
QSight 400与QSight LX50超高效液相色谱仪联用，为实验室提供全新的技术体验，用于分析复杂的食品、药品类和环境类样品。拥有超高的灵敏度和样品通量，实验室可轻松、快速和高效地应对最严格的法规监管要求。
Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements
Product Certificate for the QSight 300/400 Series
检测大麻中农药和真菌毒素的含量对于确保消费者安全和质量控制非常重要。在这项工作中，PerkinElmer应用开发团队分析了所有66种农药（包括通常通过GC-MS/MS分析的极疏水性农药和含氯农药）以及加入到大麻花提取物中的5种真菌毒素，其含量远低于加利福尼亚州规定的限值。使用配有ESI和APCI源的LC-MS/MS仪器，通过一种简单的溶剂萃取方法，所有分析物回收率均在70-120%的可接受范围内。
本文提出了一种快速、灵敏的LC/MS/MS方法。
黄曲霉毒素B1被认为是最具遗传毒性的真菌毒素，当被奶牛食用后，会转化为黄曲霉毒素M1，而黄曲霉毒素M1在某些动物身上被证明会导致肝癌。
随着一些美国的州和省通过了药用和娱乐用途合法化的新法规，大麻浓缩物和CBD产品（食用食品、主题食品、电子烟产品等）的使用越来越受欢迎。确保大麻产品中杀虫剂和真菌毒素水平低于监管水平的测试至关重要，然而，大麻浓缩物基质存在许多分析挑战，包括样品基质效应更高和样品中大麻素浓度增加。在本应用说明中，提出了一种用于分析大麻浓缩物基质中66种农药（包括通常通过GC/MS/MS分析的疏水性和含氯农药）和5种真菌毒素的LC/MS/MS方法。利用配置有APCI和ESI双源的QSight®420 LC/MS/MS仪器，分析回收率良好且检测限低于加利福尼亚州大麻法规规定的标准。 ...
以猪肉特有的三种肽为生物标志物，建立了一种选择性、灵敏的LC/MS/MS快速鉴定和分析肉样的方法。优化后的样品制备方法简单易行，可用于生、熟、加工肉制品的分析。该方法可以在1%w/w（10mg/g）的阈值检测范围内选择性地检测各种食品猪肉中的肽，因此该方法可用于清真食品（或猪肉相关食品）样品的分析。
由于具有选择性高、灵敏度高、适用于多种样品基质中多种化合物的分析等优点，液相色谱-串联质谱法（LC/MS/MS）已成为农药分析的首选方法。本研究采用改进的QuEChERS提取法与LC/MS/MS联用，建立了一种快速、灵敏、选择性好的多残留分析方法，对大米中200多种农药进行了分析。采用QSight®三重四极杆质谱仪中的时间管理MRM™，可为目标分析物多个MRM通道自动分配最佳驻留时间。这不仅节约了方法开发的时间，也提高了数据质量和分析性能，这些在本研究中的大米样品中多农药残留分析结果有具体展示。
塑料是当今全球使用量最多的材料之一。它们已广泛融入现代工业和商业生活方式，几乎对每类产品都做出了不可替代的重大贡献。
您将在本纲要中了解聚合物、塑料、橡胶和先进材料的广泛应用，以及这些应用如何简化您的工作并提升效率。
多环芳烃（PAHs）在烟熏、加热和干燥过程中会污染食品，这些过程会使燃烧产物直接接触到食品。它们还可以通过受污染的空气和水进入食物供应链，并在各种食物链中积累。相关机构制定了相关法规来监测食品中多环芳烃的含量；欧盟对熏鱼和熏制水产品肉中的BaP设定了严格的最大残留限量（MRL）为2µg/kg。在本研究中，海产品采用QueChERS萃取法，然后采用分散固相萃取净化步骤制备。随后，通过超高压液相色谱-三重四极杆质谱仪联用系统对样品进行分析。
真菌毒素是由真菌产生的有毒次级代谢产物，使谷物、玉米和谷类食品特别易受污染。基于这些因素，并考虑到估计有25%农作物有被一些霉菌毒素污染的迹象，许多国家制定了真菌毒素最大限量的监管准则，这不仅是对饲料和谷物，而且对加工食品也有要求。
随着《2018年农业改良法案》的通过，为大麻二酚（CBD）提取而进行的大麻产品农业种植在美国合法化。自该法案通过以来，对大麻生产中杀虫剂的使用备受关注。然而，美国目前没有联邦指南来标准化大麻制品中农药残留的检测和定量分析方法。 在该应用文献中，介绍了一种一针进样同时测定66种杀虫剂的稳健高效的LC/MS/MS方法，且分析物涵盖了常规情况下需要采用GC/MS/MS分析的部分疏水性农药和含氯农药。采用PerkinElmer QSight®420 (UHPLC和MS/MS检测器，双ESI/APCI源) ，可获得70-120%范围内的优良回收率。文献中还概述了参加Emerald Scientific盲 ...
为了保护人类健康，世界各地的监管机构制定了食品中兽药的最大残留水平（MRL）或允许水平。根据监管要求，使用高灵敏度和选择性的技术对四环素进行准确监测对保护人类健康至关重要。本研究提出了一种快速、灵敏的UHPLC/MS/MS方法用于肉类中四环素类抗生素的定量分析。 为了提高实验室生产率，QS Works采用了高通量自动进样器，因为它具有大容量、温控托盘和机械臂，可以长时间无人操作。QS works还允许实验室按顺序运行多达600个样本，从而提高测试实验室的效率。所开发的方法具有良好的灵敏度、线性、回收率、精密度和选择性，用于分析世界上不同监管机构设定的低耐受水平的肉类中的四环素。 ...
In this study we show two methods for the analysis of over 30 antibiotics and veterinary drugs in milk regulated by the Food Safety and Standards Authority of India (FSSAI). For polar analyte analysis, such as aminoglycoside antibiotics (apramycin, spectinomycin, and neomycin) in milk, a mixed mode ...
The increasing demand for organic products, evolving global regulations, and improving accessibility of agricultural hubs to global markets results in pressure on food safety precautions. Translating, in part, to increased pesticide residue analysis demand. Mass spectrometry meets pesticide analysis ...
Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...
Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through contami ...
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
Estrogens are steroid hormones derived from cholesterol. They are crucial for the development of female secondary sex characteristics and reproductive functions, and are also important for many other non–sex-specific processes, including growth, skeleton maintenance, cardioprotective, and neuroprote ...
Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade t ...
Simultaneous detect and quantify cortisol and cortisone in urine using the QSight 200 series mass spectrometer coupled with a commercially available kit.
Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fire-fighting foams, water proofing treatments for clothing and furniture, nonstick cookware, and paper. PFAS’ are thermally and chemically st ...
This application note outlines a new workflow with one instrument platform (LC/MS/MS) method that is ideal for simultaneous analysis of pesticide and mycotoxins residue in cannabis. This application note demonstrates the performance of a LC/MS/MS ESI and APCI method with a single solvent extraction ...
Estrogen plays an important role in the human body, but excess concentrations of endogenous estrogens, a known endocrine disrupting compound (EDC), in urine have been linked to the development and growth of breast cancer and tumors in females. Endogenous estrogens, including estrone (E1), 17ß-estrad ...
Tobacco specific nitrosamines (TSNA) are a group of chemicals found in tobacco, smokeless tobacco, and tobacco smoke. They are widely considered to be among the most important arcinogens in tobacco products and cigarette smoke. Tobacco product manufacturers must report their contents in tobacco prod ...
Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals developed in the 1940s, and widely used for their surfactant properties. Due to their prevalent use within consumer products and persistence in nature, PFAS have leached into the air, soil, and water, making exposure wides ...
Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product quality ...
Growing health concerns regarding PFAS and their prevalence in consumer goods and the environment indicate a critical need to execute existing and upcoming regulatory methods simply and reliably on commercially available instrumentation. The United States Environmental Protection Agency (EPA) has es ...
Per- and polyfluoroalkyl substances (PFAS) are a diverse group of synthetic organic compounds which have been utilized as aqueous film forming foams (AFFF) for firefighting purposes, and as stain and water resistant coatings on a number of consumer products such as clothing, furniture or cookware. P ...
This application note details an online-SPE-LC/MS/MS method for the determination of polycyclic aromatic hydrocarbons (PAHs) in drinking water samples which reaches the low detection levels required by EU regulations. The method couples the SP50 UHPLC system to the QSight® 400 series triple-quad mas ...
Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF
Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial
Demand for cannabis testing services continues to climb as more US states and countries around the globe implement regulated adult-use markets. The cannabis testing sector in the US, like many facets of the cannabis industry, is challenged by the complexity of working with a federally illegal but st ...
聚合物市场充斥着大量工业产品制造商，有着多种不同的处理工艺，但仍面临着类似的挑战。 如为了实现产品高质量并降低成本，在竞争中领先一步，他们面临着越来越大的压力。
Per- and polyfluoroalkyl substances (PFAS) have gained significant attention as an emerging environmental and safety threat in the United States. Since the 1940s, PFAS are ubiquitous in industrial usage due to their chemical stability, thermal stability, and high resistance to degradation. Bioaccumu ...
