The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| 型号名称 | QSight 420 LC/MS/MS |
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Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and the effects that they can have on human health. Due to their inert nature, PFASs are persistent organic pollutants and have been found to ac ...
Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.
With our extended portfolio of cannabis testing products featuring best-in-class sample homogenization platforms, ICP-MS, LC/MS-MS, Headspace-GCMS, UHPLC and FTIR instruments and consumables, we help drive analytical best practices and operating procedur
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.
Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.
When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.
The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.
In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing
In this latest webinar, LC–MS/MS PerkinElmer expert Dr. Avinash Dalmia describes how LC–MS/MS based systems and methods can overcome the challenges associated with the analysis of pesticides and mycotoxins regulated by Colorado state in hemp with dual ES
Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza
PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis.
Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a
In this podcast, we meet with Simone Rumph, a first generation college student, to discuss her research on post-mortem drug identification.
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..
When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.
The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC
农药可以通过我们食用的食物对人类健康产生不利影响，也可以渗入土壤和地下水并通过环境影响我们。为了适应复杂且不断变化的监管环境，您的农药分析解决方案需要跟上您不断增长的样本量。
QSight 400与QSight LX50超高效液相色谱仪联用，为实验室提供全新的技术体验，用于分析复杂的食品、药品类和环境类样品。拥有超高的灵敏度和样品通量，实验室可轻松、快速和高效地应对最严格的法规监管要求。
When analyzing food and environmental samples, laboratories often need multiple system to get the qualitative and quantitative information on contaminants. But this can result in duplicated sample preparation processes, increased cost of ownership – and suboptimal lab efficiency. Discover the unique ...
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
在养蜂业中，磺胺类药物是治疗美国和欧洲臭虫病（一种感染蜜蜂的疾病）的最常用抗生素。本应用说明介绍了QSight 200系统如何为蜂蜜中磺胺类药物的分析提供一个非常灵敏和可靠的平台。
检测大麻中农药和真菌毒素的含量对于确保消费者安全和质量控制非常重要。在这项工作中，PerkinElmer应用开发团队分析了所有66种农药（包括通常通过GC-MS/MS分析的极疏水性农药和含氯农药）以及加入到大麻花提取物中的5种真菌毒素，其含量远低于加利福尼亚州规定的限值。使用配有ESI和APCI源的LC-MS/MS仪器，通过一种简单的溶剂萃取方法，所有分析物回收率均在70-120%的可接受范围内。
水溶性维生素（WSV）主要由维生素B复合物组成，是许多食品的基本成分，尤其是在婴儿配方食品中。在分析强化食品时，由于需要符合每日的摄入量，维生素的浓度范围很广，这一点尤其具有挑战性。本应用介绍了一种LC-MS/MS方法，用于婴儿配方食品中B族维生素的高效、常规和稳定的色谱分析。很宽浓度范围内的八种水溶性维生素被鉴定出来，并在4分钟内定量。结果表明，保留时间重复性好，该方法能够在0.5 ppb的浓度下检测维生素B12，远低于婴儿配方奶粉中预期水平的约2 ppb。
本文提出了一种快速、灵敏的LC/MS/MS方法。
黄曲霉毒素B1被认为是最具遗传毒性的真菌毒素，当被奶牛食用后，会转化为黄曲霉毒素M1，而黄曲霉毒素M1在某些动物身上被证明会导致肝癌。
以猪肉特有的三种肽为生物标志物，建立了一种选择性、灵敏的LC/MS/MS快速鉴定和分析肉样的方法。优化后的样品制备方法简单易行，可用于生、熟、加工肉制品的分析。该方法可以在1%w/w（10mg/g）的阈值检测范围内选择性地检测各种食品猪肉中的肽，因此该方法可用于清真食品（或猪肉相关食品）样品的分析。
液相色谱-串联质谱（LC/MS/MS）已成为农药检测的首选方法。俄勒冈州对大麻花和大麻浓缩物中的59种农药残留量发布了监管限制，而其他州则提出了自己的与医用大麻和大麻检测有关的农药残留清单。
葡萄是世界上消费量最大的水果作物之一。葡萄既可作为新鲜产品也可作为加工产品消费，如葡萄酒、果酱、果汁、果冻、葡萄籽提取物、葡萄干、醋和葡萄籽油。在葡萄的整个生长季节，各种各样的杀虫剂被使用以控制葡萄园的病虫害和提高作物产量。由于大多数国家越来越严格的法规和安全标准，农药残留是葡萄产业利益相关者最为关注的问题。
如果葡萄酒中含有大量的农药和非法添加物，会给消费者带来健康风险。本研究建立了一种简便、灵敏的液相色谱-质谱联用（LC-MS/MS）方法，可以一针进样同时分析农药和色素。
多环芳烃（PAHs）在烟熏、加热和干燥过程中会污染食品，这些过程会使燃烧产物直接接触到食品。它们还可以通过受污染的空气和水进入食物供应链，并在各种食物链中积累。相关机构制定了相关法规来监测食品中多环芳烃的含量；欧盟对熏鱼和熏制水产品肉中的BaP设定了严格的最大残留限量（MRL）为2µg/kg。在本研究中，海产品采用QueChERS萃取法，然后采用分散固相萃取净化步骤制备。随后，通过超高压液相色谱-三重四极杆质谱仪联用系统对样品进行分析。
真菌毒素是由真菌产生的有毒次级代谢产物，使谷物、玉米和谷类食品特别易受污染。基于这些因素，并考虑到估计有25%农作物有被一些霉菌毒素污染的迹象，许多国家制定了真菌毒素最大限量的监管准则，这不仅是对饲料和谷物，而且对加工食品也有要求。
随着《2018年农业改良法案》的通过，为大麻二酚（CBD）提取而进行的大麻产品农业种植在美国合法化。自该法案通过以来，对大麻生产中杀虫剂的使用备受关注。然而，美国目前没有联邦指南来标准化大麻制品中农药残留的检测和定量分析方法。 在该应用文献中，介绍了一种一针进样同时测定66种杀虫剂的稳健高效的LC/MS/MS方法，且分析物涵盖了常规情况下需要采用GC/MS/MS分析的部分疏水性农药和含氯农药。采用PerkinElmer QSight®420 (UHPLC和MS/MS检测器，双ESI/APCI源) ，可获得70-120%范围内的优良回收率。文献中还概述了参加Emerald Scientific盲 ...
独特层流气离子导向技术UHPLC-ESI-MS/MS分析浆果中目标农药残留
In this study we show two methods for the analysis of over 30 antibiotics and veterinary drugs in milk regulated by the Food Safety and Standards Authority of India (FSSAI). For polar analyte analysis, such as aminoglycoside antibiotics (apramycin, spectinomycin, and neomycin) in milk, a mixed mode ...
Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
A simple and sensitive method for the simultaneous determination of plant growth regulators
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade t ...
Cyanotoxins often exist intracellularly in cyanobacteria and are released into the water when cells die. Blooms caused by cyanobacteria can be harmful to the human health, animals, and the environment. Microcystin-LR (MC-LR) is one of the most common cyanotoxins and ingestion will cause negative hum ...
Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fire-fighting foams, water proofing treatments for clothing and furniture, nonstick cookware, and paper. PFAS’ are thermally and chemically st ...
Estrogen plays an important role in the human body, but excess concentrations of endogenous estrogens, a known endocrine disrupting compound (EDC), in urine have been linked to the development and growth of breast cancer and tumors in females. Endogenous estrogens, including estrone (E1), 17ß-estrad ...
Tobacco specific nitrosamines (TSNA) are a group of chemicals found in tobacco, smokeless tobacco, and tobacco smoke. They are widely considered to be among the most important arcinogens in tobacco products and cigarette smoke. Tobacco product manufacturers must report their contents in tobacco prod ...
Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product quality ...
EU water policies are reevaluated on a consistent basis to ensure water sources do not contain contaminants at levels above regulatory levels. As regulations are reviewed, regulatory limits are often lowered, and analytical techniques must adapt to meet the new stringent requirements. In this applic ...
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
Per- and polyfluoroalkyl substances (PFASs), or Per- and polyfluorinated compounds (PFCs), represent a group of anthropogenic chemicals that have been produced and widely used in industrial applications and consumer products since the 1950s. The unique physical and chemical characteristics of these ...
Simulation using sophisticated modeling techniques has become a powerful tool for mass spectrometry
The COVID-19 pandemic impacted industries, economies, and lives, and brought about the need for a new approach for contract testing laboratories working in different application fields. Considering the directions shaping the laboratory industry, this article revises trends that could be also applied ...
