The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| 型号名称 | QSight 220 LC/MS/MS |
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Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and the effects that they can have on human health. Due to their inert nature, PFASs are persistent organic pollutants and have been found to ac ...
This nanometrology portfolio infographic poster gives you a 1-page overview of the instrumentation required by laboratories for the investigation of nanomaterials which are used to develop advanced materials in a range of applications.
Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.
Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.
When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.
The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.
In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing
Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza
Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..
When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.
The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC
Grains, whether consumed whole or processed, have nutritional and functional requirements and must be safe for consumption, and the only way to ensure grain quality is through rigorous testing. That’s where PerkinElmer come in. Our easy-to-operate, integrated testing and analytical solutions encompa ...
For third party food testing labs or producers who want to conduct aflatoxin M1 analysis in dairy products, our automated aflatoxin M1 ELISA assay and QSight LC/MS/MS aflatoxin M1 analyzer provide sensitive, accurate, and fit for purpose screening and confirmative analysis solutions that you can use ...
When it comes to analyzing food, cannabis, and environmental samples, we know it can be challenging to meet strict regulations that demand lower detection limits. We also know that throughput and efficiency are paramount in any accredited high-throughput laboratory. As a result, mass spectrometry is ...
This brochure provides a simple guide to the analytical solutions and supporting services we provide for forensics and toxicology laboratories. We know it's not as simple as it seems in the movies, on television, or in the latest potboiler: forensic science is an exacting science, driven by the twin ...
Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series. Our ready-to-implement solution has the highest sensitivity and throughput the industry has ever seen and the capab ...
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
Emerging contaminants include a variety of different chemical pollutants including pharmaceuticals, personal care products, endocrine disrupting compounds, per- and polyfluoroalkyl substances and others which pose a significant risk to human health. This series of drinking water analysis webinars wa ...
Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series.
Product Certificate for the QSight 110 & 120
Product Certificate for the QSight 210 & 220
本文介绍了利用UHPLC-MSMS 对河水中31种PPCPs进行定性和定量的应用。
在养蜂业中，磺胺类药物是治疗美国和欧洲臭虫病（一种感染蜜蜂的疾病）的最常用抗生素。本应用说明介绍了QSight 200系统如何为蜂蜜中磺胺类药物的分析提供一个非常灵敏和可靠的平台。
水溶性维生素（WSV）主要由维生素B复合物组成，是许多食品的基本成分，尤其是在婴儿配方食品中。在分析强化食品时，由于需要符合每日的摄入量，维生素的浓度范围很广，这一点尤其具有挑战性。本应用介绍了一种LC-MS/MS方法，用于婴儿配方食品中B族维生素的高效、常规和稳定的色谱分析。很宽浓度范围内的八种水溶性维生素被鉴定出来，并在4分钟内定量。结果表明，保留时间重复性好，该方法能够在0.5 ppb的浓度下检测维生素B12，远低于婴儿配方奶粉中预期水平的约2 ppb。
抗生素在奶牛中被用于不同的治疗，这会导致这些残留物在牛奶中积累。人类食物中存在这种残留物可能导致过敏反应、毒性反应，并产生耐药菌株。为了保护消费者，欧盟监管机构发布了一些官方文件来监管兽药。96/23/EC指令规定了食用动物的兽药残留控制。在印度，根据FSSAI（2018年7月20日的宪报公告）和EIC（水产养殖、鸡蛋、蜂蜜、奶禽等的RMP）的规定，必须对抗生素进行分析。EIC和FSSAI都有动物食品基质中各种抗生素残留的最大残留限量（MRL）。考虑到安全性和防止消费者接触兽药，对牛奶进行磺胺类药物残留检测至关重要。在这项工作中，我们提出了一种快速、灵敏的LC-MS/MS方法，用于定量分析牛奶 ...
黄曲霉毒素B1被认为是最具遗传毒性的真菌毒素，当被奶牛食用后，会转化为黄曲霉毒素M1，而黄曲霉毒素M1在某些动物身上被证明会导致肝癌。
为了保护过敏消费者的健康免受过敏原的无意或故意污染，多年来发展了检测食品中过敏原的不同分析方法。在这项工作中，我们介绍了一种使用QSight 220液相色谱-三重四极质谱仪（LC-MS/MS）同时定量分析热处理面包制品中牛奶和鸡蛋过敏原的靶向方法。
以猪肉特有的三种肽为生物标志物，建立了一种选择性、灵敏的LC/MS/MS快速鉴定和分析肉样的方法。优化后的样品制备方法简单易行，可用于生、熟、加工肉制品的分析。该方法可以在1%w/w（10mg/g）的阈值检测范围内选择性地检测各种食品猪肉中的肽，因此该方法可用于清真食品（或猪肉相关食品）样品的分析。
多环芳烃（PAHs）在烟熏、加热和干燥过程中会污染食品，这些过程会使燃烧产物直接接触到食品。它们还可以通过受污染的空气和水进入食物供应链，并在各种食物链中积累。相关机构制定了相关法规来监测食品中多环芳烃的含量；欧盟对熏鱼和熏制水产品肉中的BaP设定了严格的最大残留限量（MRL）为2µg/kg。在本研究中，海产品采用QueChERS萃取法，然后采用分散固相萃取净化步骤制备。随后，通过超高压液相色谱-三重四极杆质谱仪联用系统对样品进行分析。
真菌毒素是由真菌产生的有毒次级代谢产物，使谷物、玉米和谷类食品特别易受污染。基于这些因素，并考虑到估计有25%农作物有被一些霉菌毒素污染的迹象，许多国家制定了真菌毒素最大限量的监管准则，这不仅是对饲料和谷物，而且对加工食品也有要求。
农药被用于农作物生长中防止一些害虫和真菌的危害。当种植作物用于在畜牧业中生产饲料时，饲料中可能残留农药，对牲畜摄入农药构成风险。农药残留由多个政府机构监管，因此需要有足够稳健的分析方法来分析各种复杂基质中的分析物，同时也需要具有足够的灵敏度和选择性，以满足严格的法规要求。在本应用说明中，开发了一种快速、灵敏和高选择性的多残留分析方法，用于分析动物饲料中的94种农药，报告限值低于欧盟委员会0.01 mg/kg的最大残留限量。
β-肾上腺素受体激动剂（β-激动剂）是一种用于治疗哮喘等疾病的合成药物，在生产食品的动物中也被用作生长促进剂。出于对人类健康的考虑，许多国家都禁止或管制在生产粮食的牲畜中使用β-激动剂。为了有助于监测和检测牲畜体内的β-激动剂，本研究建立了一种高灵敏度和高选择性的分析方法。采用LC/MS/MS方法详细分析了猪肉样品中的13种β-激动剂，并利用同位素标记的内标物来补偿复杂食品基质中存在的基质效应。
本文证明了PerkinElmer QSight™ 200 系统完全满足原料乳与乳制品中三聚氰胺的日常检测工作。该系统离子源具有自清洁功能以及质谱接口HSID 热源去溶剂技术，提高仪器抗污染能力，从而获得更低的噪音，更低的检测限，从容应对复杂基质的食品安全检测。
本文证明了PerkinElmer QSight™ 210 系统完全满足动物源性食品中磺胺类药物的日常检测工作。QSight™ 210 系统，离子源具有自清洁功能以及质谱接口HSID 热源去溶剂技术，提高仪器抗污染能力，从而获得更低的噪音，更低的检测限，从容应对复杂基质的食品安全检测。
本文采用改良型QuEChERS 样品前处理方法建立了牛奶中抗生素类多残留UPLC MS/MS分析方法，该方法具有快速、稳定、可靠，高灵敏度和选择性等特点。
本文采用超高效液相色谱 - 串联质谱技术建立了燕窝中15 种激素类药物含量的检测，通过单次提取即可得到雌激素和孕激素化合物。
由于具有选择性高、灵敏度高、适用于多种样品基质中多种化合物的分析等优点，液相色谱-串联质谱法（LC/MS/MS）已成为农药分析的首选方法。本研究采用改进的QuEChERS提取法与LC/MS/MS联用，建立了一种快速、灵敏、选择性好的多残留分析方法，对大米中200多种农药进行了分析。采用QSight®三重四极杆质谱仪中的时间管理MRM™，可为目标分析物多个MRM通道自动分配最佳驻留时间。这不仅节约了方法开发的时间，也提高了数据质量和分析性能，这些在本研究中的大米样品中多农药残留分析结果有具体展示。
液相色谱-串联质谱（LC/MS/MS）已成为农药检测的首选方法。俄勒冈州对大麻花和大麻浓缩物中的59种农药残留量发布了监管限制，而其他州则提出了自己的与医用大麻和大麻检测有关的农药残留清单。
本文利用PerkinElmer Altus A-30 UPLC 与Qsight 210 三重四极杆质谱仪联用系统建立了快速，高灵敏度和可靠的LC-MS/MS 实验方法，无需衍生反应直接测定草甘膦、氨甲基磷酸和草铵膦等强极性化合物农药残留。
本文证明了PerkinElmer QSight™ 200 系统完全满足动物源性食品中雌激素类的日常检测工作。QSight™ 200 系统，离子源具有自清洁功能以及质谱接口 HSID 热源去溶剂技术，提高仪器抗污染能力，从而获得更低的噪音，更低的检测限，从容应对复杂基质的食品安全检测。
丙烯酰胺是一种可能致癌的有机化合物，存在于一些高温烹调的食物中。它源于氨基酸天冬酰胺和葡萄糖发生美拉德反应。2002年，在炸薯条和烤面包中发现了丙烯酰胺。这种化合物现在也在一些其他食物中被发现，如咖啡、黑橄榄、干梨和花生。结果是世界卫生组织立即限制了它在食品中的存在。
独特层流气离子导向技术UHPLC-ESI-MS/MS分析浆果中目标农药残留
The free amino acid content of produce, such as tomatoes, has an impact on the nutritional value and flavor characteristics of the vegetable. In this application note, the efficient and effective transfer of a commercial laboratory's in-house method to a QSight 220 LC/MS/MS for amino acid determinat ...
Drugs of abuse, which can trigger the user’s central nervous system and induce an altered state of mind, can be divided into different types, including stimulants such as cocaine, psychoactive substances such as LSD (lysergic acid diethylamide) and marijuana, and painkillers such as morphine and her ...
Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...
Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through contami ...
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
Pharmaceutical and Personal Care Products (PPCPs) are an emerging environmental concern, and include human and veterinary prescription and over-the-counter medications, sunscreens, lotions, soaps, and insect repellants. These commonly encountered products can enter the environment through various so ...
Mycotoxins are toxic secondary metabolites produced by various fungal species growing in foods and animal feeds. To minimize risk and protect consumers, mycotoxin levels in foods and/or feeds have been regulated by agencies in many countries around the world. A number of analytical methods for the d ...
Growing health concerns regarding PFAS and their prevalence in consumer goods and the environment indicate a critical need to execute existing and upcoming regulatory methods simply and reliably on commercially available instrumentation. The United States Environmental Protection Agency (EPA) has es ...
Endocrine disrupting chemicals (EDCs) have been found to have harmful effects on the health of both humans and wildlife. Of these EDCs, endogenous estrogens, such as estriol, 17ß-estriadiol, and estrone are of particular interest due to their potency/physiological activity even at very low levels. T ...
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade t ...
Since 2003 the usage of azo and non-azo dyes for food coloring has been declared as illegal by many of the food international authorities across the globe. That is because these substances such as Sudan I,II,III,IV and Rhodamine B, are potentially carcinogens and genotoxin in nature. As of now, no o ...
Simultaneous detect and quantify cortisol and cortisone in urine using the QSight 200 series mass spectrometer coupled with a commercially available kit.
Nitrosamines are a well-known group of highly potent, mutagenic impurities formed by the reaction of secondary amines with nitrite under acidic conditions. The most probable nitrosamine impurities are NDMA, NDEA, NMBA, NDBA, NDIPA, NEIPA. Following the initial observance of nitrosamine impurities in ...
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
Growing health concerns regarding Per- and polyfluoroalkyl substances (PFAS) and their prevalence in consumer goods and the environment indicates a critical need to perform existing and upcoming regulatory methods efficiently and reliably on commercially available instrumentation. The United States ...
Demand for cannabis testing services continues to climb as more US states and countries around the globe implement regulated adult-use markets. The cannabis testing sector in the US, like many facets of the cannabis industry, is challenged by the complexity of working with a federally illegal but st ...
This article, generated from a recent webinar, summarizes the most advanced methods for food contaminants determination – in particular, QSight® LC/MS/MS technology and laminar-flow mass spectrometry applied to food analysis and strategies for method optimization. Applications covered include: Multi ...
Infographic Poster showing the range of different analytical solutions for Toxicology Labs; from GC and LC, to ICP-MS and UV-Vis. Benchtop and floor standing chromatography, spectroscopy and thermal solutions for everyday robust and reliable analyses. FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC ...
Per- and polyfluoroalkyl substances (PFAS) have gained significant attention as an emerging environmental and safety threat in the United States. Since the 1940s, PFAS are ubiquitous in industrial usage due to their chemical stability, thermal stability, and high resistance to degradation. Bioaccumu ...
