The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| 型号名称 | QSight 220 LC/MS/MS |
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This nanometrology portfolio infographic poster gives you a 1-page overview of the instrumentation required by laboratories for the investigation of nanomaterials which are used to develop advanced materials in a range of applications.
Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.
Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.
When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.
The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.
In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing
Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza
Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..
When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.
The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC
珀金埃尔默公司一直致力于为用户提供整体的解决方案，在QSight系列三重四极杆液质联用系统平台开发了多项“交钥匙的解决方案” ，为公安司法行业的用户提供一站式服务。
如今，饲料加工是一项复杂的业务，农业企业无论大小都需要平衡牲畜营养和安全需求以及原料可用性与其季节性和可变性。还有加工厂提供有价值的补充和药物，很明显：您正在创造一个完整的营养分配系统，而不仅仅是一个简单的谷物混合物。
Grains, whether consumed whole or processed, have nutritional and functional requirements and must be safe for consumption, and the only way to ensure grain quality is through rigorous testing. That’s where PerkinElmer come in. Our easy-to-operate, integrated testing and analytical solutions encompa ...
For third party food testing labs or producers who want to conduct aflatoxin M1 analysis in dairy products, our automated aflatoxin M1 ELISA assay and QSight LC/MS/MS aflatoxin M1 analyzer provide sensitive, accurate, and fit for purpose screening and confirmative analysis solutions that you can use ...
When it comes to analyzing food, cannabis, and environmental samples, we know it can be challenging to meet strict regulations that demand lower detection limits. We also know that throughput and efficiency are paramount in any accredited high-throughput laboratory. As a result, mass spectrometry is ...
PerkinElmer offers a complete portfolio of analytical solutions to enable fast, accurate and intuitive testing throughout the winemaking process. Whether you're testing grapes at harvest, must during fermentation, or finished wines during the bottling process, PerkinElmer helps deliver the data you ...
Emerging contaminants include a variety of different chemical pollutants including pharmaceuticals, personal care products, endocrine disrupting compounds, per- and polyfluoroalkyl substances and others which pose a significant risk to human health. This series of drinking water analysis webinars wa ...
Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series.
水溶性维生素（WSV）主要由维生素B复合物组成，是许多食品的基本成分，尤其是在婴儿配方食品中。在分析强化食品时，由于需要符合每日的摄入量，维生素的浓度范围很广，这一点尤其具有挑战性。本应用介绍了一种LC-MS/MS方法，用于婴儿配方食品中B族维生素的高效、常规和稳定的色谱分析。很宽浓度范围内的八种水溶性维生素被鉴定出来，并在4分钟内定量。结果表明，保留时间重复性好，该方法能够在0.5 ppb的浓度下检测维生素B12，远低于婴儿配方奶粉中预期水平的约2 ppb。
抗生素在奶牛中被用于不同的治疗，这会导致这些残留物在牛奶中积累。人类食物中存在这种残留物可能导致过敏反应、毒性反应，并产生耐药菌株。为了保护消费者，欧盟监管机构发布了一些官方文件来监管兽药。96/23/EC指令规定了食用动物的兽药残留控制。在印度，根据FSSAI（2018年7月20日的宪报公告）和EIC（水产养殖、鸡蛋、蜂蜜、奶禽等的RMP）的规定，必须对抗生素进行分析。EIC和FSSAI都有动物食品基质中各种抗生素残留的最大残留限量（MRL）。考虑到安全性和防止消费者接触兽药，对牛奶进行磺胺类药物残留检测至关重要。在这项工作中，我们提出了一种快速、灵敏的LC-MS/MS方法，用于定量分析牛奶 ...
本文提出了一种快速、灵敏的LC/MS/MS方法。
黄曲霉毒素B1被认为是最具遗传毒性的真菌毒素，当被奶牛食用后，会转化为黄曲霉毒素M1，而黄曲霉毒素M1在某些动物身上被证明会导致肝癌。
为了保护过敏消费者的健康免受过敏原的无意或故意污染，多年来发展了检测食品中过敏原的不同分析方法。在这项工作中，我们介绍了一种使用QSight 220液相色谱-三重四极质谱仪（LC-MS/MS）同时定量分析热处理面包制品中牛奶和鸡蛋过敏原的靶向方法。
兽药在畜牧生产中用于治疗疾病，预防感染和保护动物的生长，这有助于提供高质量的市场。然而，不加控制的使用可能会导致严重的人类疾病，因此世界各地的监管机构都制定了食品中兽药的最大残留量（MRL）或耐受量。由于样品基质的复杂性和不同化学性质分析物的多样性，兽药残留分析通常具有挑战性。本研究中，采用溶剂萃取结合液相色谱-质谱联用技术，建立了鸡肉样品中73种兽药（包括13种不同化学类别）的快速、灵敏、选择性分析方法。
以猪肉特有的三种肽为生物标志物，建立了一种选择性、灵敏的LC/MS/MS快速鉴定和分析肉样的方法。优化后的样品制备方法简单易行，可用于生、熟、加工肉制品的分析。该方法可以在1%w/w（10mg/g）的阈值检测范围内选择性地检测各种食品猪肉中的肽，因此该方法可用于清真食品（或猪肉相关食品）样品的分析。
最近在欧洲召回受污染的鸡蛋引起了对氟虫腈中毒的严重健康担忧。氟虫腈是一种剧毒杀虫剂，用于保护农作物。美国环保署已将氟虫腈列为C组致癌物。在这项研究中，我们描述了一种快速、可靠的分析方法，采用PerkinElmer QSight 200系列LC/MS/MS三重四极杆仪器对氟虫腈及其代谢物进行鉴定。结果表明，该方法具有极佳的回收率、线性、重现性和超高灵敏度。三步法样品制备过程快速简便，LC/MS/MS分析时间可在6分钟内完成，所有分析物的分离度都很高。
β-肾上腺素受体激动剂（β-激动剂）是一种用于治疗哮喘等疾病的合成药物，在生产食品的动物中也被用作生长促进剂。出于对人类健康的考虑，许多国家都禁止或管制在生产粮食的牲畜中使用β-激动剂。为了有助于监测和检测牲畜体内的β-激动剂，本研究建立了一种高灵敏度和高选择性的分析方法。采用LC/MS/MS方法详细分析了猪肉样品中的13种β-激动剂，并利用同位素标记的内标物来补偿复杂食品基质中存在的基质效应。
本文证明了PerkinElmer QSight™ 200 系统完全满足原料乳与乳制品中三聚氰胺的日常检测工作。该系统离子源具有自清洁功能以及质谱接口HSID 热源去溶剂技术，提高仪器抗污染能力，从而获得更低的噪音，更低的检测限，从容应对复杂基质的食品安全检测。
本文证明了PerkinElmer QSight™ 210 系统完全满足动物源产品中喹诺酮类残留量的日常检测工作。该质谱系统离子源具有自清洁功能以及质谱接口HSID 热源去溶剂技术，提高仪器抗污染能力，从而获得更低的噪音，更低的检测限，从容应对复杂基质的食品安全检测。
本文证明了PerkinElmer QSight™ 200 系统具有灵敏度高、重现性好、抗污染能力强等优点，在检测动物源性食品中孕激素残留完全满足食品安全最严格的法规要求。
本文证明了PerkinElmer QSight™ 210 系统完全满足动物源性食品中磺胺类药物的日常检测工作。QSight™ 210 系统，离子源具有自清洁功能以及质谱接口HSID 热源去溶剂技术，提高仪器抗污染能力，从而获得更低的噪音，更低的检测限，从容应对复杂基质的食品安全检测。
本文采用改良型QuEChERS 样品前处理方法建立了牛奶中抗生素类多残留UPLC MS/MS分析方法，该方法具有快速、稳定、可靠，高灵敏度和选择性等特点。
本文采用超高效液相色谱 - 串联质谱技术建立了燕窝中15 种激素类药物含量的检测，通过单次提取即可得到雌激素和孕激素化合物。
本研究采用的PerkinElmer Clarus SQ 8 GC/MS ，不仅可以满足方法的要求， 为用户带来的灵活性， 还能为他们带来独一无二的高通量体验。 同时Clarifi检测器的使用还能带来拓展校正线性范围的优点。
众所周知，黑胡椒基质复杂，需要合适的提取和清除干扰的方法。本研究建立了一种快速、灵敏、选择性的多残留方法用于分析胡椒样品中超过136种农药，方法采用改进的QuEChERS提取方法与LC/MS/MS结合，利用了QSight™ 三重四极杆质谱仪中的时间管理-MRM。针对目标分析物，可自动生成多个MRM通道的最佳驻留时间。这不仅节省了方法开发的时间，而且提高了仪器的数据质量和分析性能。
葡萄是世界上消费量最大的水果作物之一。葡萄既可作为新鲜产品也可作为加工产品消费，如葡萄酒、果酱、果汁、果冻、葡萄籽提取物、葡萄干、醋和葡萄籽油。在葡萄的整个生长季节，各种各样的杀虫剂被使用以控制葡萄园的病虫害和提高作物产量。由于大多数国家越来越严格的法规和安全标准，农药残留是葡萄产业利益相关者最为关注的问题。
如果葡萄酒中含有大量的农药和非法添加物，会给消费者带来健康风险。本研究建立了一种简便、灵敏的液相色谱-质谱联用（LC-MS/MS）方法，可以一针进样同时分析农药和色素。
QSight-LC/MS/MS分析无需样品制备的葡萄酒中痕量农药。
独特层流气离子导向技术UHPLC-ESI-MS/MS分析浆果中目标农药残留
This work shows a reliable, sensitive and selective method for multi-mycotoxin determination in food samples using a PerkinElmer QSight 220 LC-MS/MS system. The method has been validated in eight different matrices and can be used in routine testing labs to meet regulatory requirements.
The free amino acid content of produce, such as tomatoes, has an impact on the nutritional value and flavor characteristics of the vegetable. In this application note, the efficient and effective transfer of a commercial laboratory's in-house method to a QSight 220 LC/MS/MS for amino acid determinat ...
Drugs of abuse, which can trigger the user’s central nervous system and induce an altered state of mind, can be divided into different types, including stimulants such as cocaine, psychoactive substances such as LSD (lysergic acid diethylamide) and marijuana, and painkillers such as morphine and her ...
This application note presents a sensitive and reliable LC/MS/MS method using the PerkinElmer QSight
Benzo[a]pyrene (B[a]P) is a well-known carcinogenic compound found in tobacco products and tobacco smoke. The Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA) has recommended a gas chromatography/ mass spectrometry (GC/MS) method to determine concentrations of B[a]P in tobacc ...
Haloacetic acids (HAAs) are a class of undesired by-products resulting from the reaction of chlorinated disinfectants with natural organic matter in water, Which is known to be carcinogenic. The Japan Ministry of Health revised the inspection method for HAAs, which led to expansion of the analytical ...
Pharmaceutical and Personal Care Products (PPCPs) are an emerging environmental concern, and include human and veterinary prescription and over-the-counter medications, sunscreens, lotions, soaps, and insect repellants. These commonly encountered products can enter the environment through various so ...
Mycotoxins are toxic secondary metabolites produced by various fungal species growing in foods and animal feeds. To minimize risk and protect consumers, mycotoxin levels in foods and/or feeds have been regulated by agencies in many countries around the world. A number of analytical methods for the d ...
Tobacco specific nitrosamines (TSNA) are a group of chemicals found in tobacco, smokeless tobacco, and tobacco smoke. They are widely considered to be among the most important arcinogens in tobacco products and cigarette smoke. Tobacco product manufacturers must report their contents in tobacco prod ...
Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product quality ...
Endocrine disrupting chemicals (EDCs) have been found to have harmful effects on the health of both humans and wildlife. Of these EDCs, endogenous estrogens, such as estriol, 17ß-estriadiol, and estrone are of particular interest due to their potency/physiological activity even at very low levels. T ...
Pesticides are utilized in a number of agricultural applications to prevent, destroy, or control harmful organisms or diseases, as well as protect plants or plant products during production, storage and transport. Although successful in these applications, pesticides can pose a risk when consumed by ...
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade t ...
Discover a fast and reliable UHPLC-MS/MS method for the determination of HVA, VMA, and 5-HIAA acid in urine using the QSight 200 series mass spectrometer and a commercially available kit.
Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fire-fighting foams, water proofing treatments for clothing and furniture, nonstick cookware, and paper. PFAS’ are thermally and chemically st ...
Nitrosamines are a well-known group of highly potent, mutagenic impurities formed by the reaction of secondary amines with nitrite under acidic conditions. The most probable nitrosamine impurities are NDMA, NDEA, NMBA, NDBA, NDIPA, NEIPA. Following the initial observance of nitrosamine impurities in ...
Coumarin (1,2-benzopyrone) occurs as a natural component in some plants, and is utilized as a flavoring ingredient in some foods, tobaccos and cosmetic products. In recent years, coumarin has been added to electronic cigarette liquid nicotine solutions as a flavoring component, producing a complex f ...
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
Growing health concerns regarding Per- and polyfluoroalkyl substances (PFAS) and their prevalence in consumer goods and the environment indicates a critical need to perform existing and upcoming regulatory methods efficiently and reliably on commercially available instrumentation. The United States ...
Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF
Demand for cannabis testing services continues to climb as more US states and countries around the globe implement regulated adult-use markets. The cannabis testing sector in the US, like many facets of the cannabis industry, is challenged by the complexity of working with a federally illegal but st ...
Predicting the long-term impact some substances have on human health and the environment is extremely difficult and in some instances we only become aware of certain substances and chemicals’ toxic impact after they have been widely used. Recently, PFAS (per- and polyfluoroalkyl substances) have bec ...
