More than ever, laboratories analyzing food and environmental samples are faced with evolving challenges with stricter regulations demanding lower detection limits and higher levels of productivity. Lab operations need to be optimized, without any compromise on analysis confidence and accuracy.
With the PerkinElmer QSight® Triple Quad LC/MS/MS labs can test for the most challenging samples with maximized uptime and confidence. The unique dual-source configuration enables high-throughput labs to collect data in two complementary modes, maximizing the output from a single injection. Combined with the StayClean™ technology dramatically reduced source cleaning and maintenance, translating into higher productivity and high ROI. Running on the PerkinElmer Simplicity™ 3Q Software, the PerkinElmer QSight Triple Quad LC/MS/MS is easy-to-learn and use and it is a complete solution streamlining the complete workflow, from validated method development to data reporting.
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The QSight LC/MS/MS System provides the capability and confidence required to analyze the most complex food and environmental samples. With high level of sensitivity and throughput, laboratories can meet even the most stringent regulatory requirements rapidly, easily, and effectively
| Model Name | QSight 220 LC/MS/MS |
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Changing the source on many an LC/MS/MS instrument from ESI to APCI, and vice versa, involves cooling the source, manual removal and installation of the new source, followed by heating of the new source to the operating temperature, resulting in low throughput for analyses utilizing both ESI and APC ...
A New, Sensitive Method for Lignan Metabolite Detection of Flaxseed-Fed Mice Using LC/MS/MS
Testing for the levels of pesticide and mycotoxins in cannabis is important to ensure consumer safety and quality control. In this work, the PerkinElmer application development team analyzed all 66 pesticides (including very hydrophobic and chlorinated pesticides typically analyzed by GC-MS/MS) and ...
Acrylamide is a probable carcinogen organic compound that is found in some foods that are cooked at elevated temperatures. It’s origins are due to the condensation of the amino acid asparagine and glucose as part of Maillard reaction. In 2002, Acrylamide was found to be present in french fries and b ...
Aflatoxin B1 is considered to be the most genotoxic of the mycotoxins, and, when ingested by cows, is converted to aflatoxin M1 which has been shown to cause liver cancer in certain animals.
Due to the large number of pesticides potentially used in rice production, the use of multi-residue methods capable of determining many pesticides in one single run is the most efficient approach. In this study, a fast, sensitive and selective multiresidue method has been developed for analysis of o ...
Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) are the two most extensively produced and studied of the per- and polyfluoroalkyl substances (PFAS) owing to their stability in the environment and toxicity to humans and wildlife. The United States Environmental Protection Agency ...
Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fire-fighting foams, water proofing treatments for clothing and furniture, nonstick cookware, and paper. PFAS’ are thermally and chemically st ...
Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide. The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with their own lists of pesticide residues rel ...
Since 2003 the usage of azo and non-azo dyes for food coloring has been declared as illegal by many of the food international authorities across the globe. That is because these substances such as Sudan I,II,III,IV and Rhodamine B, are potentially carcinogens and genotoxin in nature. As of now, no o ...
The increasing demand for organic products, evolving global regulations, and improving accessibility of agricultural hubs to global markets results in pressure on food safety precautions. Translating, in part, to increased pesticide residue analysis demand. Mass spectrometry meets pesticide analysis ...
Veterinary drugs are utilized extensively in modern day farming to prevent and treat animal diseases. However, use of these drugs must be carefully monitored, and failure to regulate the presence of residual veterinary drugs in animal tissues could pose a risk to human health if animal tissues with ...
Fipronil is a broad-spectrum phenylpyrazole insecticide almost used to protect corps from insects but also to treat lice and ticks in chickens. The U.S. EPA classified fipronil as Group C, possible human carcinogen, therefore International organizations defined admissible limits for the fipronil usa ...
Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...
Coumarin (1,2-benzopyrone) occurs as a natural component in some plants, and is utilized as a flavoring ingredient in some foods, tobaccos and cosmetic products. In recent years, coumarin has been added to electronic cigarette liquid nicotine solutions as a flavoring component, producing a complex f ...
Nitrosamines are a well-known group of highly potent, mutagenic impurities formed by the reaction of secondary amines with nitrite under acidic conditions. The most probable nitrosamine impurities are NDMA, NDEA, NMBA, NDBA, NDIPA, NEIPA. Following the initial observance of nitrosamine impurities in ...
Polycyclic aromatic hydrocarbons (PAHs) can contaminate foods during smoking, heating, and drying processes that allow combustion products to come into direct contact with food. They can also enter food supply chains through contaminated air and water, and accumulate in various food chains. Regulati ...
In this work, we present a fast and sensitive LC/MS/MS method
It is very well known that Black pepper is a complex matrix that requires a proper extraction and clean-up method for interferences. In this study, a fast, sensitive and selective multi-residue method has been developed for analysis of over 136 pesticides in Pepper samples by coupling a modified QuE ...
Drugs of abuse, which can trigger the user’s central nervous system and induce an altered state of mind, can be divided into different types, including stimulants such as cocaine, psychoactive substances such as LSD (lysergic acid diethylamide) and marijuana, and painkillers such as morphine and her ...
The free amino acid content of produce, such as tomatoes, has an impact on the nutritional value and flavor characteristics of the vegetable. In this application note, the efficient and effective transfer of a commercial laboratory's in-house method to a QSight 220 LC/MS/MS for amino acid determinat ...
Growing health concerns regarding Per- and polyfluoroalkyl substances (PFAS) and their prevalence in consumer goods and the environment indicates a critical need to perform existing and upcoming regulatory methods efficiently and reliably on commercially available instrumentation. The United States ...
Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals developed in the 1940s, and widely used for their surfactant properties. Due to their prevalent use within consumer products and persistence in nature, PFAS have leached into the air, soil, and water, making exposure wides ...
Tobacco specific nitrosamines (TSNA) are a group of chemicals found in tobacco, smokeless tobacco, and tobacco smoke. They are widely considered to be among the most important arcinogens in tobacco products and cigarette smoke. Tobacco product manufacturers must report their contents in tobacco prod ...
Governing bodies have implemented various directives to monitor acrylamide in drinking water. This also applies in the European Union where the water framework directive and subsequent daughter directives have defined many priority substances, including acrylamide. Compounds chlorate, perchlorate an ...
Sensitive and accurate determination of remdesivir and GS-441524 in human plasma samples for pharmacokinetic and pharmacodynamic studies of remdevisir.
To protect the health of allergic consumers from the inadvertent or intentional contamination by allergens, different analytical methods for the sensitive detection of allergens in food were developed over the years. In this work we present the performance of a targeted method using the QSight 220 L ...
Pesticides are employed in the growing of crops to prevent damage from a number of pests and fungi. When crops are grown to produce feed for livestock, there is a potential for pesticides residues to remain on the feeding stuffs, posing a risk to the livestock ingesting them. Pesticide residues are ...
Pesticides are utilized in a number of agricultural applications to prevent, destroy, or control harmful organisms or diseases, as well as protect plants or plant products during production, storage and transport. Although successful in these applications, pesticides can pose a risk when consumed by ...
The Grape crop is one of the most important fruit crops consumed in the world. Grapes are consumed both as fresh and as processed products, such as wine, jam, juice, jelly, grape seed extract, raisins, vinegar and grape seed oil. A large variety of pesticides are used in grape production throughout ...
Aniline and aniline derivatives are widely used as raw materials and intermediates in the polymer, rubber, dye, pesticide and pharmaceutical industries. Unintended releases of aniliane or its derivatives into the environment pose a serious threat, with release possible during any stage of production ...
Ochratoxin A (OTA) is a secondary metabolite produced by Penicillium and Aspergillus fungi species found in soil and organic matter, and is one of the most widely reported of the nearly 400 recognized mycotoxin contaminants of agricultural products. OTA can enter the human food chain through contami ...
A simple and sensitive method for the simultaneous determination of plant growth regulators
In this study, the QSight LC-MS/MS system was used to evaluate the potential of eliminating sample preparation for trace level pesticide analysis in a complex sample such as wine. We injected undiluted red and white wine samples into the mass spectrometer and studied reproducibility in analysis of t ...
The COVID-19 pandemic impacted industries, economies, and lives, and brought about the need for a new approach for contract testing laboratories working in different application fields. Considering the directions shaping the laboratory industry, this article revises trends that could be also applied ...
Liquid chromatography/tandem mass spectrometry (LC/MS/MS) is one of the most common bioanalytical methods used today, offering ultrasensitive detection in the several-partsper- million (or even parts-per-billion) range. The unique specificity of tandem mass spectrometry provides greater flexibility ...
For third party food testing labs or producers who want to conduct aflatoxin M1 analysis in dairy products, our automated aflatoxin M1 ELISA assay and QSight LC/MS/MS aflatoxin M1 analyzer provide sensitive, accurate, and fit for purpose screening and confirmative analysis solutions that you can use ...
This brochure provides a simple guide to the analytical solutions and supporting services we provide for forensics and toxicology laboratories. We know it's not as simple as it seems in the movies, on television, or in the latest potboiler: forensic science is an exacting science, driven by the twin ...
Food testing labs like yours are constantly challenged with accurately analyzing samples quickly and efficiently - all while striving to reduce costs due to market forces. Your commitment to ensuring meat and seafood are safe for consumption, as demand increases, is an uphill battle. Our commitment ...
PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis. Our robust and reliable LC/MS/MS systems along with high quality consumables and the industry’s most trusted service and application support network will deliver the throughput, produ ...
Our QSight triple quad LC/MS/MS family has always been known for its robust and reliable performance. But now there’s something new – something better: the high performance 400 series. Our ready-to-implement solution has the highest sensitivity and throughput the industry has ever seen and the capab ...
Predicting the long-term impact some substances have on human health and the environment is extremely difficult and in some instances we only become aware of certain substances and chemicals’ toxic impact after they have been widely used. Recently, PFAS (per- and polyfluoroalkyl substances) have bec ...
Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and the effects that they can have on human health. Due to their inert nature, PFASs are persistent organic pollutants and have been found to ac ...
Emerging contaminants include a variety of different chemical pollutants including pharmaceuticals, personal care products, endocrine disrupting compounds, per- and polyfluoroalkyl substances and others which pose a significant risk to human health. This series of drinking water analysis webinars wa ...
Demand for cannabis testing services continues to climb as more US states and countries around the globe implement regulated adult-use markets. The cannabis testing sector in the US, like many facets of the cannabis industry, is challenged by the complexity of working with a federally illegal but st ...
This nanometrology portfolio infographic poster gives you a 1-page overview of the instrumentation required by laboratories for the investigation of nanomaterials which are used to develop advanced materials in a range of applications.
Infographic Poster showing the range of different analytical solutions for Toxicology Labs; from GC and LC, to ICP-MS and UV-Vis. Benchtop and floor standing chromatography, spectroscopy and thermal solutions for everyday robust and reliable analyses. FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC ...
Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting
Lab reequirements for QSight triple quad LC/MS/MS systems, including storage, suppleis, space, electrical, power, gas supply requirements
Product Certificate for the QSight 110 & 120
Product Certificate for the QSight 210 & 220
Simulation using sophisticated modeling techniques has become a powerful tool for mass spectrometry
Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial
Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.
Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.
PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.
PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.
As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.
Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.
When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.
The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.
In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing
Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza
Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a
In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.
Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..
When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.
The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC
