Regulatory Compliance and Quality Control Testing Solutions in Cannabis & Hemp | PerkinElmer
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Cannabis regulatory compliance analysis solutions

Regulatory Compliance and Quality Control Testing Solutions in Cannabis & Hemp

Protecting human health is of primary importance when it comes to cannabis and hemp products. During the different stages of growth and manufacturing, cannabis and hemp products can come into contact with a number of contaminants that can be potentially harmful to consumers.

 

With the legalization of cannabis for medical and recreational applications ever increasing globally, the demand for clean and safe cannabis and related products has grown significantly. It is, in fact, agreed that cannabis products should be regulated as any other product intended for human consumption. Regulatory compliance ensures that consumers are receiving harmless and free from contaminants products. Whether you need to identify and quantify pesticides and mycotoxins or measure the amount of heavy metal content of plants, PerkinElmer can be your single-source partner for your quality control testing solutions.

For years, we have been working with government and cannabis contract laboratories to develop industry-leading methods with our extensive portfolio.

Regulatory Compliance Testing Solutions Related Content

Pesticide and Mycotoxin Testing

Testing to ensure that pesticide and mycotoxin levels in cannabis products are below regulatory levels is critical, as the cannabis concentrate matrix presents many analytical challenges including higher sample matrix effects and an increased concentration of cannabinoids in the sample. High performance liquid chromatography-tandem mass spectrometry (LC/MS/MS) has emerged as the method of choice for pesticide and mycotoxin analysis as it offers superior selectivity, sensitivity, ruggedness, and does not require extensive sample preparation before analysis for a wide panel of analytes.

Our QSight® LC/MS/MS can analyze pesticides (including hydrophobic and chlorinated pesticides typically analyzed by GC/MS/MS) and mycotoxins in a cannabis concentrate matrix. Thanks to the dual APCI and ESI sources, you can get detection limits below those specified by the states cannabis regulations with a single instrument.

Moreover, we are now capable of offering you our QS-Works 420, the fully automated cannabis sample preparation workflow, which includes the ONE Pesticide420 reagent kit, JANUS® G3 420 Workstation, QSight® 420 LC/MSMS, integrated SimplicityLab420 software for data management, and cannabis specific SOPs, ensures that only the highest quality of cannabis products reach the consumer.

PerkinElmer Cannabis & Hemp Analytical Solutions App Note Compendium

This compendium explores how mass spectrometry can interrogate cannabis in record time, detecting heavy metals, pesticides and residual solvents – all highly harmful to consumers in substantial amounts. In terms of desirable compounds, modified mass spectrometry techniques can also be harnessed to d ...

A Single Cannabis Method to Meet California Pesticide and Mycotoxin Residues Regulatory Requirements

Testing for the levels of pesticide and mycotoxins in cannabis is important to ensure consumer safety and quality control. In this work, the PerkinElmer application development team analyzed all 66 pesticides (including very hydrophobic and chlorinated pesticides typically analyzed by GC-MS/MS) and ...

QS-Works 420 Complete Automated Workflow for Potency, Pesticide, and Mycotoxin Testing in Cannabis and Hemp

QS-Works 420 represents the first ever connected suite of technology and reagents developed solely for supporting the cannabis and hemp testing market. Included in the workflow is a holistic laboratory execution system (LES), which integrates data across all instruments to allow scientists to proces ...

Analysis of Pesticides and Mycotoxins in Cannabis and Hemp with the ONE Pesticide420™ ISO17034 CRM Reagent Kit

To help laboratories reduce their turn around time, and improve their overall efficiency and data quality, PerkinElmer has developed the ONE Pesticide420™ ISO 17034 Reagent Kit for labs that operate in accordance with the California, Oregon, or equivalent regulatory requirements. In this study, mult ...

Efficient LC/MS/MS Method for Testing Hemp Samples for Pesticide Residues

Agricultural growing of hemp products for the purposes of cannabidiol (CBD) extraction was legalized in the United States with the passing of the Agricultural Improvement Act of 2018. Since the act passed, heightened concern over the use of pesticides in hemp production has been appreciated. However ...

Meeting Canadian Cannabis Pesticide Residues Regulatory Requirements by LC/MS/MS

Following the 2018 legalization of recreational cannabis usage in Canada, the quality and safety of cannabis products has garnered significant attention. Health Canada has developed a regulatory program mandating pesticide testing on all cannabis products. Under the program, licensed producers (LPs) ...

Novel ESI and APCI LC/MS/MS Method for Testing Cannabis and Hemp Concentrate Samples

The use of cannabis concentrates and CBD products (edibles, topicals, vape products, etc.) has increased in popularity as new regulation has been passed legalizing medicinal and recreational use in a number of states and provinces. Testing to ensure that pesticide and mycotoxin levels in cannabis pr ...

Analysis of Pesticide Residues in Cannabis Regulated by Oregon State Using LC/MS/MS

Liquid chromatography-tandem mass spectrometry (LC/MS/MS) has become the method of choice for pesticide. The state of Oregon has issued regulatory limits for 59 pesticide residues in both cannabis flower and concentrates, while other states have come up with their own lists of pesticide residues rel ...

LC/MS/MS Analytical Method for Pesticide Residue in Cannabis Flower as Defined by Florida Testing Requirements

This application note outlines a new workflow with one instrument platform (LC/MS/MS) method that is ideal for simultaneous analysis of pesticide and mycotoxins residue in cannabis. This application note demonstrates the performance of a LC/MS/MS ESI and APCI method with a single solvent extraction ...

Quantitation of Pesticide and Mycotoxin Residues in Cannabis as Defined by Seven States Recreational Cannabis Regulations

This application note describes a novel LC/MS/MS method with dual ESI and APCI source for analysis of different pesticides and mycotoxins residues regulated by seven different states in cannabis samples as of June 2021. The straightforward sample preparation procedure allows to achieve short sample ...

Heavy Metals Testing

Heavy Metals can be absorbed into the cannabis plant and, even if at trace levels, they can still be harmful to end consumers. As such, it’s important to measure the toxic or nutritional elemental content of the cannabis sample. To help ensure accuracy and compliance, our Titan MPS and NexION ICP-MS include detailed state and matrix-specific methods that allows heavy metals such as Mercury, Lead, Arsenic, and Cadmium, and nutritional elements such as copper, zinc, and iron to be quantified in a cannabis lab.

Partner with us to have access to four decades of patents, innovations, and accolades in ICPMS technology that only PerkinElmer has.

PerkinElmer Cannabis & Hemp Analytical Solutions App Note Compendium

This compendium explores how mass spectrometry can interrogate cannabis in record time, detecting heavy metals, pesticides and residual solvents – all highly harmful to consumers in substantial amounts. In terms of desirable compounds, modified mass spectrometry techniques can also be harnessed to d ...

Digestion, Testing, and Validation of Heavy Metals in Cannabis

Owing to the toxicity of heavy metals, it is increasingly important to test cannabis flowers and other cannabis derivatives so that patient and consumer safety is maintained as the use of cannabis becomes more common. This need has translated into an increasing demand for testing cannabis flowers an ...

Residual Solvents & Terpene Testing

Terpenes are a class of compounds found in the oils of all plants and botanicals and are responsible for their unique flavors and aromas. Terpene profiles are diverse and can vary significantly depending on factors such as temperature, growth medium, nutrients and sunlight. This complexity makes accurate and reliable methods for testing and analysis important for consumers, healthcare professionals, and growers to ensure the quality and consistency of the cannabis is documented and labelled accurately.

The extraction process of cannabinoids and terpenes from the plant material involves the use of solvents. Solvents are used to extract the cannabinoids and terpenes from the plant material. The procedure can also create impure byproducts, which may not be completely removed from the final product. These residual solvents can be toxic. The determination and understanding of terpenes and residual solvents concentrations are critical phases of cannabis testing for both health safety and product quality. The PerkinElmer HS-GC/MS solution for the determination of terpenes is fast and robust providing the laboratory with greater sample throughput, instrument uptime, and enhanced profits.

Our GC/MS-HS solution for Residual Solvents is fast and capable of quantifying residual solvents in all cannabis matrices. Combined with essentially maintenance-free operation, a PerkinElmer’s GC/MS-HS method will enhance productivity and strengthen your cannabis lab’s business operations.

PerkinElmer Cannabis & Hemp Analytical Solutions App Note Compendium

This compendium explores how mass spectrometry can interrogate cannabis in record time, detecting heavy metals, pesticides and residual solvents – all highly harmful to consumers in substantial amounts. In terms of desirable compounds, modified mass spectrometry techniques can also be harnessed to d ...

Fast, Accurate, and Precise Terpene Testing of Cannabis Samples

Like all botanicals and plants found in nature, cannabis also contains terpenes, which are the aromatic oils that give rise to the distinctive flavors and aromas found in cannabis varieties. There have been up to 140 different types of terpenes reported in cannabis, but multiple studies suggest that ...

Fast, Quantitative Analysis of Residual Solvents in Cannabis Concentrates

Compared to the more traditional cannabis flower, cannabis concentrate products, such as extracts, tinctures, edibles, waxes, and oils are becoming the most commonly used cannabis products that are legally manufactured for both medicinal and recreational purposes. Most concentrates are extracted usi ...

Potency Testing

Potency testing allows the quantitation of THC and CBD and other major cannabinoids, which is essential for quality products and precise labelling of cannabis products.

When it comes to measuring cannabis potency, HPLC is considered to be gold standard. Our HPLC- photodiode array method has been rewarded with the Potency in Solution award from The Emerald Test, a well-regarded inter-laboratory comparison and proficiency test program for cannabis and hemp testing facilities.

If you’re looking for shorter sample preparation and user-friendly solution Fourier Transform Near-Infrared (FT-NIR) spectroscopy is the technique of choice. NIR instruments use infrared light to analyze materials by measuring the proportion of light that is reflected by the sample. Higher concentrations of compounds absorb more infrared light and therefore reflect less to the NIR instrument. In FT-NIR spectroscopy, sample analysis time is reduced using an infrared beam that contains many frequencies of light (polychromatic) at once. This enables all wavelengths to be measured simultaneously.

PerkinElmer Cannabis & Hemp Analytical Solutions App Note Compendium

This compendium explores how mass spectrometry can interrogate cannabis in record time, detecting heavy metals, pesticides and residual solvents – all highly harmful to consumers in substantial amounts. In terms of desirable compounds, modified mass spectrometry techniques can also be harnessed to d ...

Optimization of the Decarboxylation Reaction in Cannabis Extract

Most cannabis extraction processes, independent of solvent or instrument choice, undergo a decarboxylation step whereby the carboxylic acid functional group is removed from the cannabinoids. The PerkinElmer Spectrum Two with the UATR accessory allows for the simple and rapid determination of cannabi ...

Analysis of 16 Cannabinoids Using the PerkinElmer LC 300 HPLC System with PDA Detection

Accurate identification and quantification of cannabinoid content is a critical step in the process to bringing safe and high quality cannabis flower and fortified products to market. As the legalization of recreational cannabis use continues throughout the world, fast and efficient liquid chromatog ...

Analysis of Cannabinoids in Hemp Seed Oils by HPLC Using PDA Detection

In this application, we describe a technique for the monitoring of six cannabinoids, including THC and CBD, in hemp seed oil by HPLC with PDA detection. Figure 1 shows the chemical structures for the six cannabinoids. In recent years, scientific knowledge regarding the composition and health benefit ...

Pathogen & Microbial Testing

Our products and solutions are intended to be used for analytical testing of cannabis in laboratories where such use is permitted under state and/or country law. We do not support or promote the use of its products or solutions in connection with illegal use. Further, we are not condoning the use of recreational or medical marijuana.

PerkinElmer Cannabis & Hemp Analytical Solutions App Note Compendium

This compendium explores how mass spectrometry can interrogate cannabis in record time, detecting heavy metals, pesticides and residual solvents – all highly harmful to consumers in substantial amounts. In terms of desirable compounds, modified mass spectrometry techniques can also be harnessed to d ...

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