NexION 5000 Multi-Quadrupole ICP Mass Spectrometer | PerkinElmer
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NexION 5000 Multi-Quadrupole ICP Mass Spectrometer

R&D 100 Award winner NexION 5000 ICP-MS

The first in its category to boast four quads, the NexION® 5000 multi-quadrupole ICP-MS is innovatively designed to meet and exceed the demanding requirements of ultra-trace elemental applications. It delivers exceptionally low background equivalent concentrations and outstanding detection limits, key to ensuring accurate, repeatable results. Plus, it provides superior interference removal, phenomenal stability and unmatched matrix tolerance, for results you can count on. Discover how the NexION 5000 takes ICP-MS performance beyond traditional triple quad.

In addition to boasting four quads, the NexION 5000 is also the proud recipient of three awards: Wiley Analytical Science Award, The Analytical Scientist Innovation Award, and R&D 100 Award.

Part Number
Model Name
Technology Type
N8160010
NexION 5000 Cleanroom ICP-MS
Multi-Quad ICP-MS for Cleanroom Applications
more
N8160009
NexION 5000 Non-Cleanroom ICP-MS
Multi-Quad ICP-MS for Non-Cleanroom Applications
more
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Overview

The NexION 5000 Non-Cleanroom ICP-MS is highly recommended for applications which do not require the use of a cleanroom, but which still benefit from the unmatched sensitivity and interference removal capabilities of the NexION 5000 series. It features a host of new and proprietary technologies that deliver outstanding detection limits, astounding accuracy, excellent repeatability and the long-term stability required by your applications:

  • Four quadrupoles:
    • First: Quadrupole Ion Deflector (Q0) directs ions to the entrance of the first mass filter
    • Second: Transmission Analyzer Quadrupole 1 (Q1, full-sized for <0.7 amu mass resolution), acts as a mass filter or as an ion guide to direct ions to the Quadrupole Universal Cell
    • Third: Quadrupole Universal Cell (Q2), empowered by dynamic bandpass tuning, prevents side reactions with residual reaction gases in the cell
    • Fourth: Transmission Analyzer Quadrupole 2 (Q3, full-sized for <0.7 amu mass resolution), acts as a mass filter or as an ion guide to direct ions to the detector
  • Extended Dynamic Range (EDR) increases linear dynamic range to 1014, allowing the accurate analysis of both high- and low-concentration analytes in a single analytical run, resulting in fewer re-runs
  • Low maintenance for greater uptime:
    • Triple Cone Interface with patent-pending OmniRing combined with Quadrupole Ion Deflector deliver no maintenance beyond cones, for continual operation and improved stability
    • 34 MHz free-running RF generator offers trouble-free user experience - the plasma is generated by the unique LumiCoil RF load coil, which is air cooled (does not require water or gas cooling), so maintenance-free, eliminating need to replace plasma load coils
  • External status lighting provides easy visibility of state of analysis, optimizing efficiencies
  • Syngistix for ICP-MS software (v. 3.0 or higher) brings together the power of the triple-quad ion optics with automated startup, optimization, batch analysis and shutdown, user-friendly workflows, and more in a contemporary user interface

Specifications

Depth 85.0 cm
Height 85.0 cm
Model Name NexION 5000 Non-Cleanroom ICP-MS
Product Brand Name NexION
Technology Type Multi-Quad ICP-MS for Non-Cleanroom Applications
Weight 191.0 kg
Width 114.0 cm
Resources, Events & More
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Application Brief

Determination of Heavy Metals in Cassava Flours Using NexION ICP-MS Following U.S. FDA EAM 4.7 Method

Cassava is a root vegetable and a major source of calories and carbohydrates in many countries around the globe. As one of the most important staple crops, its levels of harmful chemicals and pathogens are strictly controlled – these include organic chemicals and heavy metals. Metals, such as cadmiu ...

PDF 1 MB
Determination of Organotin in Tap Water by HPLC-ICP-MS in Accordance with Chinese Method HJ 1074-2019

Organotin compounds are widely used across industry and agriculture, resulting in widespread pollution of various environmental media, including potable water. Among these compounds are tributyltin (TBT), triphenyltin (TPT), dibutyltin (DBT), and diphenyltin (DPT), in the following order of persiste ...

PDF 506 KB
PM10 and PM2.5 Air Pollution Monitoring and Source Apportionment in Asia Using the NexION ICP-MS

Concern about air pollution has been growing rapidly, with most of the focus on gaseous pollutants. Airborne particulates, especially small ones, are rapidly gaining attention due to their impact on human health, as smaller particles can be carried over long distances by wind and penetrate deep into ...

PDF 1 MB

Application Note

Analysis of Blood Using NexION 5000 ICP-MS

For many years, inductively coupled plasma mass spectrometry (ICP-MS) has been the tool of choice for the trace analysis of elements like lead (Pb), arsenic (As), mercury (Hg), and copper (Cu) in bodily fluids such as urine, blood, serum and saliva, as well as in tissues. Blood and serum are two com ...

PDF 1 MB
Analysis of Samples Rich in Rare Earth Elements Prepared by Lithium Borate Fusion on the NexION 5000 ICP-MS

Rare earth elements (REEs) have many uses in the advanced technology and electronics that are utilized in automobiles, airplanes, camera lenses, medical devices, televisions, smartphones, and computers, to name a few. With the growing demand for REEs to support technological advancement, the search ...

PDF 1 MB
Determination of Bromine in Ultra-High-Purity Copper using the NexION 5000 ICP-MS

Copper (Cu) is widely used due to its high electrical and thermal conductivity, strong corrosion resistance, excellent workability and moderate strength. It is one of the few metals used most commonly in its pure form, and ultra-pure copper specifically is the standard material used in the bonding w ...

PDF 1 MB
Determination of Impurities in Lithium Materials with the NexION 5000 ICP-MS

The capability to identify the presence of impurities in lithium (Li) battery materials is critical for manufacturers and suppliers to ensure that the performance of the final battery is not compromised. Li salts used in battery production are generally extracted from brines and, subsequently, have ...

PDF 639 KB
Determination of Selenium Species in Drinking Water by HPLC-ICP-MS

Selenium (Se) is an essential element at trace levels, toxic at higher levels, and exists in several oxidation states in a variety of inorganic and organic compounds. Consequently, the chemistry of selenium is complex in both the environment and biota. For the determination of selenium species in wa ...

PDF 907 KB
Determination of Toxic and Other Trace Elements in Baby Foods Using the NexION ICP-MS

For many children around the globe, commercial baby foods are the main source of nutrients and energy, and therefore their quality and safety are critical and must be monitored. In March 2021, the U.S. House of Representatives introduced the “Baby Food Safety Act of 2021” to regulate the presence of ...

PDF 699 KB
Direct Analysis of Trace Elements in Open-Ocean Seawater using the NexION 5000 ICP-MS

Due to high total dissolved solids (TDS), seawater is considered one of the most difficult matrices to analyze for the presence of heavy metals and other trace elements. Plus, trace elements in open-ocean seawater are even lower than in coastal areas, thus are more challenging to accurately measure ...

PDF 1 MB
Direct Determination of Rare Earth Impurities in High-Purity Gadolinium Oxide with the NexION 5000 ICP-MS

Gadolinium (Gd) is commonly used in the production of magnetic compounds. Another application is in Mg-Gd-based alloys, which are used primarily for their excellent corrosion-resistance properties, and it is for this reason that they can be used in many other applications which require high-strength ...

PDF 1 MB
Direct Determination of Rare Earth Impurities in High-Purity Neodymium Oxide with the NexION 5000 ICP-MS

Since the purity of the rare earth elements (REEs) governs their efficacy and the price, it is of great interest to produce ultra-high purity rare earth oxides. Neodymium oxide (Nd2O3) is one such REE and is mainly used as a colorant for glass and ceramics, a raw material for the manufacture of meta ...

PDF 1 MB
Direct Determination of Rare Earth Impurities in High-Purity Ytterbium Oxide with the NexION 5000 ICP-MS

Rare earth elements (REEs) are crucial components in many advanced materials for industrial use, as well as consumer electronics. As the properties and prices of REEs are dependent on their purity, it is of great interest to produce rare earth oxides of high purity. High-purity ytterbium oxide (Yb2O ...

PDF 1 MB
Direct Determination of Trace Rare Earth Impurities in High-Purity Europium Oxide using the NexION 5000 ICP-MS

Rare earth elements (REEs) exhibit many optical, electrical, and magnetic properties, and therefore play an irreplaceable role in high-tech photoelectromagnetic materials. At present, the widely used color TV phosphors, Ni-H batteries, high-performance magnetic materials, etc. are all examples of ra ...

PDF 1 MB
Direct Determination of Trace Rare Earth Impurities in High-Purity Praseodymium Oxide with the NexION 5000 ICP-MS

Rare earth elements (REEs) are often referred to as "industrial vitamins", as they are used in a variety of traditional industrial fields as well as in new materials. A particularly important application of some REEs, for example high-purity praseodymium oxide (Pr6O11), is their use in optoelectroni ...

PDF 1 MB
Direct Trace-Element Analysis in Cell Culture Media and Raw Materials with the NexION 5000 ICP-MS

Raw material preparation and formulation is a known source of elemental content and variation in cell culture media. Other sources of trace metal concentrations and variability include the leaching of trace metals from bioreactors, preparation vessels and storage containers. Quality control in cell ...

PDF 756 KB
Measurement of Impurities in High-Purity Copper Concentrate using the NexION 5000 ICP-MS

Most of the copper (Cu) concentrates produced globally contain some impurities, which can affect the price as copper concentrates containing high levels of impurities are not accepted by some smelters. To permit treatment and to maximize the value of a Cu concentrate, the levels of impurities in the ...

PDF 1 MB
Elemental Analysis of Urine Using the NexION 5000 ICP-MS

Inductively coupled plasma mass spectrometry (ICP-MS) has become the preferred method for detecting trace-level amounts of elements like lead, arsenic, mercury, and copper in bodily fluids such as urine, blood, saliva, and tissue.

Application Note
Elemental Analysis of Serum Using the NexION 5000 ICP-MS

Inductively coupled plasma mass spectrometry (ICP-MS) has become the go-to technique for the trace analysis of elements such as nickel (Ni), arsenic (As), mercury (Hg) and copper (Cu) in bodily fluids. However, blood and serum present a common hurdle in

Application Note
Analysis of Silicon Isotope Ratios Using the NexION 5000 ICP-MS

Silicon (Si), the second most abundant element in the earth’s crust, has three stable isotopes: 28Si, 29Si, and 30Si, with natural abundances of approximately 92.23%, 4.67%, and 3.1%, respectively.

Application Note

Article

Bottled Lightning: Researching and Designing Better Batteries with the Help of ICP-OES, ICP-MS, and FTIR Analysis

Article by Kieran Evans on researching and designing better batteries with the help of ICP-OES, ICP-MS, and FTIR Analytical methods in a laboratory setting

Article

Blog

How to Bring a Better ICP-MS to Market (and Win a Few Awards)

The NexION® 5000 multi-quadrupole ICP-MS won an R&D 100 Award, recognizing it as, “One of the 100 most technologically significant new products of the year in the analytical/test category.”

Blog

Brochure

Comprehensive Forensic Analysis Solutions

This brochure provides a simple guide to the analytical solutions and supporting services we provide for forensics and toxicology laboratories. We know it's not as simple as it seems in the movies, on television, or in the latest potboiler: forensic science is an exacting science, driven by the twin ...

PDF 1 MB
NexION 5000 Multi-Quadrupole ICP-MS - Interactive Brochure

In the fast-paced analytical world, accurate and reproducible results are essential to guaranteeing quality and ensuring safety. What many industries have in common is the need for trace-element analysis with superior interference removal, extremely low detection limits, and outstanding background e ...

PDF 2 MB

Ebook

New Developments in Multi-Quadrupole ICP-MS Technology for Challenging Applications

Laboratories conducting trace-elemental analyses require high-performance instrumentation capable of delivering accurate and reproducible results, even at low concentrations. Find out how recent developments in multi-quadrupole ICP-MS technology address these evolving needs. Advantages: superior int ...

PDF 3 MB

Flyer

NexION 5000 ICP-MS – Innovation Recognized

Perfect for your most challenging applications, the cutting-edge, multi-award-winning NexION® 5000 Multi-Quadrupole ICP-MS is the industry’s first and only four-quadrupole ICP-MS instrument – taking performance well beyond everyday triple-quad technology. And the scientific community is taking notic ...

PDF 204 KB
Semiconductor & Electronics Analysis Overview Flyer

Download this Flyer for an overview of PerkinElmer's analytical solutions for the Semiconductor industry. This 2-page flyer outlines semiconductor and microelectronic workflows and applications, and the precise and reliable PerkinElmer solutions to address them - including instrumentation, consumabl ...

PDF 1 MB
Supporting Sustainability with the NexION ICP-MS Series

Today’s sustainable solutions are opening exciting new ways for businesses to fuel economic growth, while minimizing adverse impact on people and the planet. Laboratories are also working sustainability into their business plans to reduce downtime, waste, and costs – and in many cases, improve their ...

PDF 587 KB

Guide

Atomic Spectroscopy - A Guide to Selecting the Appropriate Technique and System

Atomic spectroscopy is a family of techniques for determining the elemental composition of an analyte by its electromagnetic or mass spectrum. Several analytical techniques are available: Atomic absorption (AA): flame and graphite furnace Inductively coupled plasma optical emission spectroscopy (ICP ...

PDF 3 MB
NexION 5000 ICP-MS Preparing Your Lab

This document provides information to assist in preparing your laboratory for the PerkinElmer NexION® 5000 ICP-MS system prior to instrument delivery and installation.

PDF 1 MB
NexION ICP-MS Series - Superior Interference Removal, Accurate Results

Accurate, reproducible trace elemental analysis is essential to ensuring the quality and safety of our products and our environment, and the award-winning NexION® ICP-MS platform delivers that level of accuracy and repeatability through a host of unique features that provide superior interference re ...

PDF 2 MB
NexION ICP-MS Series Consumables & Supplies Guide

Whether looking for sample introduction components or standards, we have the consumables you need to keep your NexION up and running smoothly and efficiently.

PDF 1 MB

Infographic

Solid-State Batteries Materials Analysis

We are supporting scientists as they work to solve the battery challenges that will drive the next phases of global economic advancement as the world pivots towards a renewable energy future.

Infographic

Product Note

High Throughput System for ICP-MS and ICP-OES Product Note

Our High Throughput System (HTS) is a uniquely designed modular sample introduction that integrates with the NexION® series of ICP-MS and the Avio® series of ICP-OES to dramatically reduce sample-to-sample time, thereby improving sample throughput while maintaining operation simplicity. The HTS maxi ...

PDF 1 MB
NexION 5000 Multi-Quadrupole ICP-MS

The NexION® 5000 is a multi-quadrupole-based ICP-MS instrument engineered to remove the most complex interferences, ideal for multi-element analysis applications requiring ultra-trace-level detection. Download this product note to discover all of its innovative features.

PDF 760 KB
Syngistix for ICP-MS Software - Revving Up the User Experience

Syngistix™ for ICP-MS software for the NexION® ICP-MS instruments is designed to improve efficiencies in the laboratory. It features a refreshed user interface that conforms to your workflow, delivering a modern, streamlined experience based on familiar left-to-right navigation and a ribbon menu, wi ...

PDF 778 KB

Regulatory Compliance Certification

Product Certificate - Nexion 5000

Product Certificate for the Nexion 5000

PDF 137 KB

Technical Note

All Matrix Solution System for NexION ICP-MS Platforms

PerkinElmer’s All Matrix Solution (AMS) system provides a number of benefits to simplify analysis of high-matrix samples with the NexION family of ICP-MS instruments. It allows online gas dilution, improving efficiency and preventing contamination, delivering up to 200x dilution and the ability to s ...

PDF 1 MB
Interferences in ICP-MS: Do we still have to worry about them?

Interferences will always occur in ICP-MS and need to be dealt with. However, the NexION® 5000 multi-quadrupole ICP-MS with quadrupole Universal Cell is able to effectively and reproducibly remove spectral interferences leading to improved accuracy, repeatability and reproducibility, while solving p ...

PDF 1 MB
Novel Interface for NexION 2200/5000 ICP-MS Systems – Innovative Design, Uncompromised Performance

The innovative design of the second-generation Triple Cone Interface with patent-pending OmniRing™ was developed for the NexION® 2200 and 5000 ICP-MS systems with both sensitivity and stability in mind. It builds on the Triple Cone Interface geometry of the NexION series and provides unique solution ...

PDF 706 KB
Novel Interference Removal Opportunities with the NexION 5000 ICP-MS

The NexION® 5000 ICP-MS, with multi-quadrupole technology and Universal Cell, is able to take full advantage of element reactivity with 100% pure gases by analyzing them as cluster ions at higher masses where no interferences reside, and the background is clean. The Universal Cell, thanks to its qua ...

PDF 2 MB
TotalQuant Analysis in NexION ICP Mass Spectrometers

TotalQuant, a software feature unique to PerkinElmer's NexION® ICP-MS systems, intelligently interprets the complete mass spectrum, providing semi-quantitative to quantitative results for all elements. TotalQuant and survey scan can provide supplementary and confirmatory information about unknown sa ...

PDF 1 MB
Unlocking Carbon-13 with Single Particle ICP-MS: Feasibility Study for Microplastic Detection

Carbon is difficult to measure with ICP-MS because of its high ionization potential and its presence in both the argon used to generate the plasma (primarily in the form of CO2, as an impurity) and in reagents, including acids and water. As a result, extremely high backgrounds exist at both of the n ...

PDF 1 MB
NexION ICP-MS Series Universal Cell Technology – For the Next Generation of Analysis

Interferences in plasma-based spectroscopy are among the most challenging aspects of method development for ICP-MS analysis. When complex matrices are present, polyatomic and isobaric interferences can lead to inaccurate and inconsistent results.

Technical Note

Training

Video

Syngistix for ICP-MS Software for the NexION Series Instruments

Syngistix™ for ICP-MS software for the NexION® ICP-MS series instruments is designed with your workflow in mind to make it easy for you to set up and report your analyses, upleveling your experience.

Video
Customer Spotlight: Colorado State University presents "The Periodic Table of Food"

Take a look at the exciting initiative that Colorado State University is leading: The Periodic Table of Food database.

Video
Empowering Sustainability: Renewable Energy, Batteries and Energy Storage

PerkinElmer is empowering sustainability for a range of global industries including renewable energy, batteries and energy storage.

Video

Webinars

Atomic Webinar Resources Hub

Our atomic spectroscopy experts have complied a series of Atomic Spectroscopy Webinars to walk through the fundamentals and theory of AA, ICP-OES and ICP-MS analysis.

Webinars
Materials Analysis Challenges for Battery Recyclers

Watch now to help you drive the development of more circular input structures by finding the best laboratory analysis solutions for material reclaim and reuse.

Webinars
Technology Critical Element Extraction: Transforming E-Waste into Environmental and Industrial Opportunities

In this webinar, hear from the Institute of General and Analytical Chemistry research team at Montanuniversität Leoben (MUL) in Austria. Speakers will outline their research work on identifying and quantifying TCEs (Technology Critical Elements) found in

Webinars
Power Up Your Lithium Battery Quality with ICP-OES and ICP-MS

From the electronics we interact with daily and increasingly the vehicles we travel in, lithium-based batteries are required in greater quantities with higher quality control requirements.

Webinars
Impurity Analysis in Electronic Specialty Materials (ESMs)

We all know Chips are essential for a host of day to day products which need memory and operating semiconducting chips in their manufacture - from phones to cars, to commercial and industrial equipment.

Webinars
Mining Symposium: Driving the EV Industry for Success

In this virtual symposium, the series of webinars and resources are focused on important advances in mining market macrotrends, analytical testing techniques, and their applications.

Webinars
Ocean Nutrients and Sargassum Blooms: How analytical advances drive ocean science discoveries

Disruptions in ocean chemistry can lead to algal blooms which can pose a risk to wildlife.

Webinars
Understanding Your Samples for ICP-MS – Part 2: The Advantages of Survey Scan

Syngistix™ software for NexION® ICP-MS instruments provides several different ways of data acquisition, depending on analysis needs and desirable results.

Webinars
Understanding Your Samples for ICP-MS – Part 1: The Power of TotalQuant

Syngistix™ software for NexION® ICP-MS instruments provides several different ways of data acquisition, depending on analysis needs and desirable results.

Webinars
Inline Intelligent Electronic Chemicals Quality Monitoring Series

In this on-demand presentation video, Jess Liu of NewFast Technology talks about trace contaminant detection in chip (silicon wafer) manufacturing.

Webinars
Carbon by ICP-MS? Detecting Microplastics by Single Particle ICP-MS

Plastic is a global problem due to its ubiquity and persistence in the environment. It is estimated that approximately 10% of all plastic produced ends up as fragments of different sizes in aquatic systems. Single particle inductively coupled plasma mass

Webinars
Multi-Quadrupole ICP-MS: Pushing Limits of Detection to the Next Decimal

In this webinar we will examine the power of PerkinElmer's latest in the NexION Series of ICP-MS: the NexION 5000 multi-quadrupole ICP-MS.

Webinars
Laser Ablation ICP-MS: Precise High-Throughput Analysis of Rare Earth Elements

With the increasing demand for high-specification electronic devices, the discovery of rare earth elements (REEs) has become crucial.

Webinars
Technologies for the Measure of REEs, from Exploration to Refining & Recycling

In this on-demand webinar, Dr. Diane Beauchemin, Ph.D. from University of Montreal discusses established and future promising technologies for measuring Rare Earth Elements (REEs) through the value chain of mining.

Webinars
The Role of Advanced & Nanomaterials in the Development of Battery Materials

Hear Gerlinde Wita's presentation at NanoLytica 2022 which was held at Simon Fraser University in Canada.

Webinars
Practical Approaches to Metals Analysis of Cell Culture Media by ICP-MS

In this webinar, Dr. Robert Thomas, CSci, CChem, FRSC, and Principal Consultant at Scientific Solutions focuses on the benefits of a novel multi-quadrupole ICP-MS system to mitigate common polyatomic spectral interferences found in cell culture media sam

Webinars

White Paper

The Determination of Metals in Non-Medical Face Masks

With the onset of the COVID-19 pandemic, the use of face masks by the general public has become a critical personal protective measure to minimize person-to-person transmission. While health care workers use medical or surgical masks, the general population uses non-medical, otherwise known as hygie ...

PDF 683 KB